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Χατζάκη Αικατερίνη
Αναπληρώτρια Καθηγήτρια
Εργ. Φαρμακολογίας, Τμήμα Ιατρικής, Δημοκρίτειο Πανεπιστήμιο Θράκης
Τηλ.: 25510-30541   Fax: 25510-30541   Email: achatzak@med.duth.gr  
Δ/νση Επικοινωνίας:
Εργ. Φαρμακολογίας, Τμήμα Ιατρικής, Δημοκρίτειο Παν/μιο Θράκης, Δραγάνα, 681 00 Αλεξανδρούπολη

Ακαδημαϊκά Ενδιαφέροντα:
Assistant Professor in Pharmacology, Medical School, Democritus Univ. Thrace, Greece.



Ερευνητικά Ενδιαφέροντα:
General research interest is orientated in the elucidation of the biological role of neuropeptides in the periphery, especially their involvement in the physiology of the reproductive and the digestive system. In particular,
- the anatomical distribution of Corticotropin Releasing Factor (CRF) Receptors and their ligands in reproductive and digestive tissues (endometrium, ovaries, stomach, intestine, liver) and their involvement in different aspects of their physiology (growth, apoptosis, endometrial decidualization, inflammation) and in the aetiology of human disease (for example stress-related disorders of the gut i.e. gastric ulcers, colitis, irritable bowel syndrome, etc),
- the physiology and pathophysiology of endometrium, hormonal control, autocrine/paracrine regulatory mechanisms, decidualization, angiogenesis, immune control etc. and the formation of the foetal-placental unit,
- autocrine/paracrine effects of opioid peptides in peripheral systems (endometrium, adrenals),
- the role of Gonadotropin Releasing Hormone (GnRH) and its receptors in the normal and malignant growth of the human endometrium,
- carcinogenesis and tumour markers of hormone-dependent malignancies and development of gene therapy technology for targeting hormone-dependent malignancies
- the molecular modelling of G-protein coupled receptors (GPCRs).
The studies related to the above topics are addressed using a wide spectrum of cell and molecular biology techniques (establishment of in vitro experimental models, cell culture, antibody development, immunohistochemisty and imaging, RT-PCR, receptor binding and signalling assays etc).

© Ελληνική Εταιρεία Φαρμακολογίας 2004